Skimune® is more than just an immunotoxicity assay!

May 12, 2023

Immune cell infiltration is important for inflammation because it is an integral part of the immune response, which is the body’s natural defence mechanism against pathogens and other harmful stimuli. When tissues become inflamed, immune cells are recruited to the site of inflammation to eliminate the source of the problem and initiate the healing process.

The infiltration of immune cells into the inflamed tissue is mediated by various chemokines and cytokines that are produced in response to inflammation. These molecules act as signals that attract immune cells from the bloodstream to the site of inflammation. Once they arrive, the immune cells can identify and attack pathogens, remove damaged tissue, and promote tissue repair.

However, excessive or prolonged immune cell infiltration can also contribute to tissue damage and chronic inflammation, which can lead to a range of diseases, including autoimmune disorders and cancer. Some medications can affect the immune system and potentially contribute to chronic inflammation or other immune-related conditions.

Skimune is a cutting-edge solution for measuring immune cell infiltration (such as T-cells) into tissues as a response to inflammation, sensitivity and hypersensitivity, providing invaluable insights into the immune response and its impact on tissue inflammation. With its high sensitivity and specificity, Skimune is the ideal tool for studying the complex mechanisms underlying inflammatory diseases, and for developing new therapeutic strategies to treat these conditions. Whether you’re a researcher working in immunology, drug development, or clinical diagnostics, Skimune is a must-have solution for your toolbox. With its unparalleled precision and reliability, Skimune is sure to transform the way you study T cell infiltration and inflammation.

CD3+ T-cells infiltrate into Skimune® tissues in response to an induced hypersensitivity reaction.

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