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Reference and Patents

Patents:

European Patent: 2524227
UK Patent Application: 130348.5
International Filed Patent: PCT/GB2011/052312 Skin Explant Assay
US Patent application no 13/989,581 Skin Explant Assay

References:

  1. Ahmed SS, Wang XN, Fielding M, Kerry A, Dickinson I, Munuswamy R, Kimber I, Dickinson AM. An in vitro human skin test for assessing sensitization potential. J Applied Tox (2016) 36:669-684. https://www.ncbi.nlm.nih.gov/pubmed/26251951
  2. Mavin E, Ahmed SS, O’Boyle G, Turner B, Douglass S, Norden J, Collin M, Ali S, Dickinson A, Wang XN. Regulatory T cells inhibit CD8(+) T-cell tissue invasion in human skin graft-versus-host reactions. Transplantation. 2012 Sep
  3. Ruffin N, Ahmed SS, Osorio LM, et al. The involvement of epithelial Fas in a human model of graft versus host disease. Transplantation (2011) 91(9):946-51. http://www.ncbi.nlm.nih.gov/pubmed/21403589
  4. Wang XN, Collin M, Sviland L, Marshall S, Jackson GH, Schulz U, Holler E, Karrer S, Greinix H, Elahi F, Hromadníková I, Dickinson AM. Skin explant model of human graft-versus-host disease: Prediction of clinical outcome and correlation with biological risk factors. Biol Blood Marrow Transplant (2006) 12(2):152-159. http://www.ncbi.nlm.nih.gov/pubmed/16443513
  5. Wang XN, Lange C, Schulz U, Sviland L, Eissner G, Oliver KM, Jackson GH, Holler E, Dickinson AM. IL-10 modulation of alloreactivity and graft versus host reactions Transplantation (2002), 74(6):772-778. http://www.ncbi.nlm.nih.gov/pubmed/12364854
  6. Jarvis M, Schulz U, Dickinson AM, Sviland L, Jackson G, Konur R, Wang XN, Hromadníková I, Kolb HJ, Eissner G, Holler E. The detection of apoptosis in a human in vitro skin explant assay for graft versus host reactions. Journal of Clinical Pathology (2002) 55(2):127-132. http://www.ncbi.nlm.nih.gov/pubmed/11865008
  7. Dickinson AM, Wang XN, Sviland L, Vyth-Dreese FA, Jackson GH, Schumacher TN, Haanen JBAG, Mutis T, Goulmy E. In situ dissection of the graft-versus-host activities of cytotoxic T cells for minor histocompatibility antigens. Nature Med (2002) 8(4):410-414. http://www.ncbi.nlm.nih.gov/pubmed/11927949
  8. Sviland L, Hromadníková I, Sedlácek P, Cermáková M, Stechová K, Holler E, Eissner G, Schultz U, Kolb HJ, Jackson GH, Wang XN, Dickinson AM. Histological correlation between different centres using the skin explant model to predict graft-versus-host disease following bone marrow transplantation. Hum Immunol (2001), 62(11):1277-1281. http://www.ncbi.nlm.nih.gov/pubmed/11704291
  9. Hromadníková I, Sedlácek P, Starý J, Vavrinek J, Cermáková M, Stechova K, Houbova B, Vitek A,. Sajdova J, Sviland L, Dickinson AM. Skin explant assay – an in vitro graft versus host disease predictive test for allogeneic haematopoietic stem cell transplant. Journal of Czech Physicians (2001) ;140(3):73-78.
  10. Hromadníková I, Sedlácek P, Starý J, Cermáková M, Vavrinec J, Stechová K, Dolezalová L, Sviland L, Dickinson AM. An in vitro skin explant assay as a predictive assay for graft-versus-host disease in a cohort of pediatric transplants. Pediatr Transplantation (2001) 5:258-265. http://www.ncbi.nlm.nih.gov/pubmed/11472604
  11. Dickinson AM. Predicting graft versus host disease in bone marrow transplants using in vitro techniques. In the European Commission Publication “Examples of Demonstration Projects in the Life Sciences Programmes-Vol. 3” Eds. Wakolbinger W , Jarvenpaa M, Le Dour O, Norstedt I, Aguilar A. (2000) 49-51.
  12. Dickinson AM, Wang XN, Sviland L. In vitro models of graft-versus-host disease: In Cord Blood Characteristics: Role in stem cell transplantation. Eds. Cohen SBA, Gluckman E, Rubinstein P, Madrigal JA. Published by Martin Dunitz (1999) (5) 97-127.
  13. Sviland L and Dickinson AM. A human skin explant model for predicting graft-versus-host disease following bone marrow transplantation. A Review. J. Clin. Path (1999) 52(12):910-913. http://www.ncbi.nlm.nih.gov/pubmed/10711254
  14. Wang XN, Sviland L, Ademokun AJ, Dunn J, Proctor SJ, Dickinson AM Cellular alloreactivity of human cord blood cells detected by T-cell frequency analysis and a human skin explant model. Transplantation (1998) 66(7):903-909. http://www.ncbi.nlm.nih.gov/pubmed/9798701
  15. Dickinson AM, Wang XN, Sviland J, Jackson G, Taylor P, Dunn J, Proctor SJ. Predicting graft versus host disease in HLA identical bone marrow transplants. A comparison of T cell frequency analysis and a human skin explant model. Transplantation (1998) 66(7):857-863. http://www.ncbi.nlm.nih.gov/pubmed/9798694
  16. Dickinson AM,Sviland L, Jackson G, Dunn, Stephens, Proctor SJ. Monoclonal anti-TNFa suppresses graft vs Host Disease reactions in an in vitro human skin model. (1994) 6 (2): http://www.ncbi.nlm.nih.gov/pubmed/8031996
  17. Dickinson AM, Sviland L, Jackson G, Usher P, Taylor P, Dunn J, Hamilton PJ, Proctor SJ. Cytokine involvement in predicting clinical graft versus host disease (GvHD) in allogeneic bone marrow transplant recipients. Bone Marrow Transplant (1994) 13(1):65-70. http://www.ncbi.nlm.nih.gov/pubmed/8019455
  18. Dickinson AM, Sviland L, Dunn J, Carey P, Proctor SJ. Demonstration of direct involvement of cytokines in graft versus host reactions using an in vitro human skin explant model. Bone Marrow Transplant (1991) 7:209- 216. http://www.ncbi.nlm.nih.gov/pubmed/1829387
  19. Sviland L, Dickinson AM, Carey PJ, Pearson ADJ, Proctor SJ. An in vitro predictive test for clinical graft versus host disease in allogeneic bone marrow transplant recipients. Bone Marrow Transplant (1990) 5:105-109. http://www.ncbi.nlm.nih.gov/pubmed/1968774
  20. Dickinson AM, Sviland L, Carey PJ, Reid MM, Hamilton PJ, Pearson ADJ, Proctor SJ. Skin explant culture as a model for cutaneous graft-versus-host disease in humans. Bone Marrow Transplant (1988) 3:323-329. http://www.ncbi.nlm.nih.gov/pubmed/2971410

 

 

 

 

 

 

 

 

 

 

 

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